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JAMA Dermatology Clinicopathological Challenge
February 2016

Linear Scars in a 4-Week-Old Girl

Author Affiliations
  • 1Department of Dermatology and Venereology, University of Cologne, Kerpenerstr 62, 50937 Köln, Germany
  • 2Institute for Human Genetics, University of Freiburg, Breisacherstr 33, 79106 Freiburg, Germany

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Dermatol. 2016;152(2):209-210. doi:10.1001/jamadermatol.2015.4191

A 4-week-old girl with linear scars was referred for further investigation. At birth, the child had erosions on her left leg, left side of the neck, abdomen, and left ear, and these were treated with acyclovir, cefuroxim, and gentamycin until a possible viral or bacterial infection could be ruled out. The patient was otherwise healthy and developed normally. The parents were not consanguineous and had another healthy daughter.

The clinical examination of the patient at the age of 4 weeks revealed erythematous atrophic streaks along Blaschko lines and several soft skin-colored papules on the left leg (Figure, A). An atrophic skin lesion was seen on the right abdomen that resembled striae distensae. Syndactyly of the third and fourth finger on the left hand, and subtle facial asymmetry were also noted. A skin biopsy from a soft papule was obtained and sent for histopathological evaluation (Figure, B).

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