Venous leg ulcers (VLUs) affect 2.2% of Americans older than 64 years, costing the US health care system roughly $14.9 billion annually.1 The lower extremity venous system is part of the calf muscle pump, and dysfunction (chronic venous insufficiency [CVI]) can cause ulceration).2,3 Reduced ankle range of motion (AROM), alone, or in conjunction with other factors such as CVI, can lead to calf muscle-pump dysfunction and subsequently to sustained ambulatory venous pressures, which is an integral factor in venous ulcerogenesis.3,4 Patients with VLUs have reduced AROM compared with patients diagnosed with venous disease without ulcers, or those without venous disease. Patients diagnosed with VLUs also have undiagnosed neuropathy.3,5 Compression therapy has been shown to improve healing of VLUs.4 The purpose of this study is to elucidate how compression therapy—standard care for VLUs—affects pain, neuropathy, and AROM, and how these variables relate to each other. We hypothesized that compression will reduce leg circumference and improve pain, AROM, and neuropathy.
Fox JD, Baquerizo-Nole KL, Freedman JB, Liu S, Van Driessche F, Yim E, Kirsner RS. Ankle Range of Motion, Leg Pain, and Leg Edema Improvement in Patients With Venous Leg Ulcers. JAMA Dermatol. 2016;152(4):472-474. doi:10.1001/jamadermatol.2015.5637