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JAMA Dermatology Clinicopathological Challenge
June 2016

Eruptive Reddish-Yellow Coalescing Papules in the Axillae of a Middle-Aged Man

Author Affiliations
  • 1Department of Dermatology, University of California Irvine Medical Center, Irvine
JAMA Dermatol. 2016;152(6):715-716. doi:10.1001/jamadermatol.2016.0190

A 55-year-old man presented with eruptive and painless reddish-yellow papules in the axillae (Figure, A and B). He endorsed polyuria and polydipsia but was otherwise asymptomatic. The patient’s medical history included hypertension, and review of his family medical history was noncontributory. Recent extensive laboratory data revealed mildly elevated triglycerides (209 mg/dL [to convert to mmol/L, multiply by 0.0113]) but otherwise were all within normal limits. On physical examination, numerous coalescing reddish-yellow pedunculated papules were present in both axillae (Figure, A and B). No other cutaneous lesions were present. Shave biopsy of one of the left axillary papules was performed (Figure, C and D) with additional immunohistochemistry positive for CD68 antibody staining.

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