Staphylococcus simulans is a common animal pathogen that occasionally can colonize human skin.
A man in his 60s with a history of hypertension and diabetes mellitus, who worked as a butcher and occasional hunter and had contact with hares and rabbits, presented with lesions on left hand evolving over 3 days. Initially, vesiculobullous lesions appeared on the dorsal aspect of his left hand and extended into the web space between the first and second fingers (Figure, A). Within 2 days, the lesion extended to the palm and ventral aspect of the thumb with an eroded area on which pustules appeared (Figure, B). No fever or other systemic symptoms were present.
Tous Romero F, Gutiérrez García-Rodrigo C, Velasco Tamariz V, Llamas Martín R. Acute Infection by Staphylococcus simulans in the Hand of a Man. JAMA Dermatol. 2016;152(9):1060. doi:10.1001/jamadermatol.2016.0959