The original study1 that proposed the “Tyndall effect” as the explanation behind the coloration of blue nevi drew from spectrophotometric data on cadaveric skin and not the direct study of blue nevi. Since then, the moniker of the Tyndall effect has been applied to a variety of blue phenomena in the skin despite a lack of confirmatory data. We hypothesized that other light-skin optical characteristics may provide a better explanation for the visual phenomenon associated with why blue nevi appear blue.
Shive M, Ho D, Lai O, Mamalis A, Miller KM, Jagdeo J. The Role of Subtractive Color Mixing in the Perception of Blue Nevi and Veins—Beyond the Tyndall Effect. JAMA Dermatol. 2016;152(10):1167-1169. doi:10.1001/jamadermatol.2016.2201