Do antiseptics and antibiotics benefit surgical wounds healing by secondary intention (SWHSI)?
No high-quality randomized clinical trials have addressed this question. Current evidence is limited and insufficient; it is uncertain whether treating SWHSI with antiseptics or antibiotics is beneficial.
Norman G, Dumville JC, Crosbie EJ. Antiseptics and Antibiotics for Surgical Wounds Healing by Secondary IntentionSummary of a Cochrane Review. JAMA Dermatol. 2016;152(11):1266-1268. doi:10.1001/jamadermatol.2016.3131