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October 2016

History of Podophyllin

Author Affiliations
  • 1Department of Dermatology, Keserwan Medical Center affiliated with AUBMC, Beirut, Lebanon
JAMA Dermatol. 2016;152(10):1105. doi:10.1001/jamadermatol.2015.6301

Podophyllotoxin is the principal active compound from the resin mixture known as podophyllin. It is obtained from 1 of the 3 species of Podophyllum: P peltatum (from North America), P hexandrum (from India; previously referred to as P emodi), or P pleianthum (from Taiwan).1Podophyllum peltatum is an indigenous, North American, herbaceous perennial flowering in May and bearing fruit in late summer or fall. Other common names include May apple, mandrake, Indian apple, wild lemon, and duck's foot.1

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