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JAMA Dermatology Clinicopathological Challenge
November 16, 2016

Cutaneous Nodules and Erythematous Plaques on the Extremities

Author Affiliations
  • 1The PhD Program in Clinical and Translational Science, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy
  • 2Division of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy
  • 3Centro Traumatologico Ortopedico, Department of Orthopaedic Oncology and Reconstructive Surgery, University Hospital Careggi, Florence, Italy
JAMA Dermatol. Published online November 16, 2016. doi:10.1001/jamadermatol.2016.3966

A healthy man in his 20s presented with a several-month history of asymptomatic, slightly erythematous cutaneous nodules, measuring 1.5 to 3.0 cm, over the calcanea (Figure, A). Physical examination revealed violaceous plaques, measuring 2 to 3 cm, on the extensor surface of the knees, bilaterally (Figure, B). Excisional biopsy specimens were obtained (Figure, C and D).

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