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January 11, 2017

Prurigo Pigmentosa in White Monozygotic Twins

Author Affiliations
  • 1Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
JAMA Dermatol. Published online January 11, 2017. doi:10.1001/jamadermatol.2016.4921

Prurigo pigmentosa (PP) is a rare acquired inflammatory dermatosis with peculiar clinical and histological features. The disease, which predominantly occurs in young women, has been most frequently reported in Japan. In a review of the literature, we found only a few cases of PP in non-Japanese patients compared with more than 300 in Japanese patients.1 Although ethnicity and environmental factors have been claimed to play a role in the pathogenesis of PP, so far no cause has been identified for this striking eruption. We describe monozygotic white twins who both developed PP.

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