The skin biopsy specimen revealed a dense inflammatory cell infiltrate throughout the papillary dermis that was composed of polymorphonuclear neutrophils and lymphocytes. There was no evidence of leukocytoclastic vasculitis, such as deposits of fibrinoid material around the capillaries, disruption of the vessel structure, or extravasation of erythrocytes. Oral prednisone therapy was initiated at a dosage of 1 mg/kg. Fifteen days later, only residual erythema was noted, and the fever and conjunctivitis had subsided.
Erythematous Plaques With Fever and Leukocytosis—Diagnosis. Arch Dermatol. 2005;141(2):263-268. doi:10.1001/archderm.141.2.264-a