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July 2005

Possible Mechanisms in the Induction of Pemphigus Foliaceus by Topical Imiquimod Treatment

Arch Dermatol. 2005;141(7):908-909. doi:10.1001/archderm.141.7.908

We welcome the article by Lin et al,1 “Localized Pemphigus Foliaceus Induced by Topical Imiquimod Treatment,” the first case report of imiquimod-induced localized pemphigus foliaceus. Only 2 months after this first case report, a second one was published.2 We would like to address several aspects of the possible mechanisms involved in the induction of pemphigus foliaceus by topical imiquimod treatment.

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