August 2005


Author Affiliations

Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005

Arch Dermatol. 2005;141(8):1051-1053. doi:10.1001/archderm.141.8.1051

The hypereosinophilic syndrome (HES) is a heterogeneous group of conditions characterized by hypereosinophilia and organ dysfunction caused by eosinophil-mediated tissue damage.1 The most common histopathologic findings in patients with HES with papular lesions is a dermal perivascular infiltration consisting of eosinophils and mononuclear cells. True necrotizing vasculitis is rare.1 We describe herein 2 patients with HES who experienced hypereosinophilia with cutaneous necrotizing eosinophilic vasculitis in association with deep vein thrombosis (DVT) of the lower extremities.

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