Microscopic examination revealed unencapsulated mature adipose tissue enveloped in fibrous sheaths, consistent with PCFH. No features of neurofibromatosis or immature mesenchymal components, such as brown fat, were identified.
The pedal nodules were resected. Grossly, the nodules were composed of lipomatous material in discrete 2- to 3-mm spheres. There was little cohesion between the individual “caviarlike” lipomatous spheres, and they were easily removed. Three weeks after resection, the patient was walking normally without any apparent discomfort.
Bilateral Plantar Nodules in an Infant—Diagnosis. Arch Dermatol. 2005;141(9):1161-1166. doi:10.1001/archderm.141.9.1161-h