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October 2005

Purple Polypoid Masses on the Legs—Diagnosis

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Arch Dermatol. 2005;141(10):1311-1316. doi:10.1001/archderm.141.10.1311-f

The biopsy specimen from the leg nodule showed hyperkeratosis and acanthosis of the epidermis and well-circumscribed spindle cell nodules in the dermis. Within these dermal nodules, there were characteristic slitlike spaces with surrounding ectatic vessels. The pathologic findings were consistent with KS.

Further workup included sigmoidoscopy with biopsies of red nodules in the rectum, and the clinical findings were suggestive of mucosal lesions of KS. However, histologic examination showed only focal acute cryptitis. Bronchoscopic examination with lavage of several suspicious erythematous lesions in the bronchial tree did not show any features of malignancy or viral cytologic change.

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