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We appreciate the helpful comments of Levy and colleagues. The very recent results from studies of Navarro et al,1,2 subsequent to submission of our manuscript, on mutations in the LMNA and ZMPSTE24 genes are indeed important findings for elucidating the etiology of restrictive dermopathy (RD).
Armbrust S, Hoffmann R, Jochum F, Neumann LM, Fusch C. Defective Prelamin A Processing Resulting From LMNA or ZMPSTE24 Mutations as the Cause of Restrictive Dermopathy—Reply. Arch Dermatol. 2005;141(11):1473-1474. doi:10.1001/archderm.141.11.1474-a