JAMES M.GRICHNIKMD, PhD
The lesion presented is from the dorsal surface of the left foot of a 21-year-old Italian man. Clinical and dermoscopic images were obtained at baseline (Figure 1 and Figure 2) and 14 months later (Figure 3 and Figure 4). The lesion grew in a symmetrical manner, increasing in size about 3-fold. An evolution of dermoscopic pattern was noted. At baseline, the lesion revealed a symmetrical regular “negative” globular pattern with underlying blue-brown homogeneous pigmentation. After 14 months, the lesion revealed a confluence of the “negative” globular pattern forming dirty-tan “cobblestone” structures centrally outlined with white-blue rims. Surface scaling was also noted. The lesion was excised at this point, and the diagnosis of deep-penetrating nevus was rendered. To date, clinical images of deep-penetrating nevi are rare; to our knowledge, dermoscopic features have not been previously presented.
Guadagni M, Nazzari G. Clinical and Dermoscopic Features of an Evolving Deep-Penetrating Nevus. Arch Dermatol. 2005;141(11):1490. doi:10.1001/archderm.141.11.1490