December 2005

The Skinny on Psoriasis and Obesity

Author Affiliations

Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005

Arch Dermatol. 2005;141(12):1601-1602. doi:10.1001/archderm.141.12.1601

Obesity seems to be common in patients with psoriasis. The relationship is somewhat unclear, although in our experience, many patients at our clinic have some degree of obesity. Furthermore, recent trials of biologic therapy for treatment of psoriasis have commonly enrolled subjects with weights in excess of 90 kg (198 lb). Evidence for a link between psoriasis and obesity exists: medications developed for patients with diabetes mellitus are undergoing clinical trials for patients with psoriasis,1 and dietary modification can improve symptoms of psoriasis.2,3 Finally, patients with psoriasis and those who are obese share certain comorbidities, such as type 2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular disease.4

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