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January 2006

A Case of Undetermined Tropical Ulceration Involving the Nose, Pharynx and Larynx, With Histological Findings

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Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Dermatol. 2006;142(1):12-13. doi:10.1001/archderm.142.1.12

By JOHN A. FORDYCE, M.D.Professor of Dermatology and Syphilology, University and Bellevue Hospital Medical College, New York City.

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I have often shown well marked cases of yaws to non-professional persons, in order to observe what their descriptions of the tubercles would be; and I have never yet observed anyone to omit to compare them to raspberries [Figure], whence, of course, frambæsia. Charlouis hoped vainly to lessen confusion in a locality where the pathological condition that occupies us seems to have been non-existent by replacing the opposite term frambæsia with a histologically descriptive and a locative name. Jeanselme’s personal investigations in Cochin China and Annam (reported at the meeting of the British Medical Association in July, 1905), and Cannac’s and Montel’s admirable and exact clinical contributions regarding yaws, appear to establish this disease as independent of syphilis. Doubtless, as A. Le Dentu says, the alleged sequels of yaws and their relations to syphilis, may not be convincingly discussed until the whole question of tropical syphilis is elucidated; and I think that it may well be admitted that this great field has been up to the present, if not entirely untilled, but little more than scratched.

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