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February 2006

BCG Granuloma Appearing More Than 50 Years After Vaccination

Arch Dermatol. 2006;142(2):243-253. doi:10.1001/archderm.142.2.249

Although the effectiveness of vaccination with BCG, an attenuated strain of Mycobacterium tuberculosis, has been challenged,1,2 the vaccine has been used in Japan since 1942. We describe a very rare case of a patient in whom BCG granuloma was identified by polymerase chain reaction (PCR)–based genomic deletion analysis more than 50 years after vaccination for BCG.