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March 2006

Erosive Velvety Lesion on the Vulva—Quiz Case

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Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Dermatol. 2006;142(3):385-390. doi:10.1001/archderm.142.3.385-c

A 100-year-old Japanese woman presented with a genital erosive skin lesion that she had noticed 3 years earlier. On physical examination, a 50 × 30-mm whitish-pink velvety lesion was observed on the right vulva (Figure 1). The indurated lesion showed a small central erosion measuring 10 × 10 mm. Inguinal lymph nodules were not palpable. A skin biopsy specimen was obtained from the center of the eroded lesion (Figure 2), and an initial diagnosis of genital Paget disease was made.