The successful treatment of 6 cases of lentigo maligna (LM) with topical imiquimod was recently reported by Wolf et al.1 We describe a 78-year-old woman with an extensive recurrent LM (melanoma in situ) that completely regressed after 12 weeks of topical imiquimod therapy. Dermoscopic analysis was useful to confirm the initial diagnosis and to monitor treatment efficacy.
Micantonio T, Fargnoli MC, Peris K. Usefulness of Dermoscopy to Monitor Clinical Efficacy of Imiquimod Treatment for Lentigo Maligna. Arch Dermatol. 2006;142(4):523-533. doi:10.1001/archderm.142.4.530-b