A 57-year-old man presented with a 6-month history of a reddish nodule on his glans penis. He stated that about 2 years earlier he had been treated with electrocoagulation for a whitish verrucoid papule at the same location on his body. The clinical diagnosis at that time was penile wart. About 1 year later, the patient noticed a slowly enlarging nodule at the same site on his penis.
Physical examination revealed a reddish nodule, measuring approximately 1 cm in greatest diameter, on the right side of the glans penis (Figure 1) The nodule had an irregular border and a smooth surface. The lesion was never pruritic or otherwise symptomatic. The inguinal lymph nodes were not palpable, and the results of the rest of the physical examination were within normal limits. A chest radiograph and an abdominal sonogram revealed no abnormalities. A biopsy specimen of the glans was obtained (Figure 2 and Figure 3).
Betti R, Menni S, Crosti C. A Reddish Nodule on the Glans Penis—Quiz Case. Arch Dermatol. 2006;142(4):515-520. doi:10.1001/archderm.142.4.515-c