Hematoxylin-eosin–stained sections of the punch biopsy specimen showed a vascular proliferation within the dermis that was composed of spindled endothelial cells diffusely infiltrating the collagen fibers as well as areas with a more lobular architecture. Rare mitotic figures were seen.
Our patient received intravenous methylprednisolone and vincristine therapy in the hospital. Within 3 weeks, he was discharged with instructions to return for weekly infusions of vincristine and tapering doses of methylprednisolone. At his most recent follow-up, 5 months after initial presentation, he was clinically stable with no significant bleeding episodes. The tumor has showed partial reduction in size as a result of treatment.
Abdominal Plaque in a 10-Day-Old Boy—Diagnosis. Arch Dermatol. 2006;142(5):641-646. doi:10.1001/archderm.142.5.641-f