Question: For adults and children with atopic dermatitis, which are more effective and better tolerated in reducing the signs and symptoms of atopic dermatitis: topical pimecrolimus, tacrolimus, corticosteroids, or vehicle?
Design: Systematic review and meta-analysis.
Data Sources: Electronic searches of the Cochrane Library database, MEDLINE, and EMBASE.
Study Selection: Randomized controlled trials of topical pimecrolimus or tacrolimus reporting efficacy outcomes or tolerability.
Bigby M. Tacrolimus and Pimecrolimus for Atopic DermatitisWhere Do They Fit In?. Arch Dermatol. 2006;142(9):1203-1205. doi:10.1001/archderm.142.9.1203