In the last few years, several biologic agents acting on tumor necrosis factor (TNF) α and intercellular adhesion molecule 1 have been considered as possible treatments for alopecia areata (AA),1 despite clinical trials of some biologic agents such as etanercept, efalizumab, and alefacept showing no significant hair regrowth in AA. We report herein 2 cases of acute AA occurring during treatment with biologic agents.
Tosti A, Pazzaglia M, Starace M, Bellavista S, Vincenzi C, Tonelli G. Alopecia Areata During Treatment With Biologic Agents. Arch Dermatol. 2006;142(12):1650-1666. doi:10.1001/archderm.142.12.1653