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December 2006

Pseudomonas aeruginosaEcthyma Gangrenosum and Facial Cellulitis Complicating Carbimazole-Induced Agranulocytosis

Arch Dermatol. 2006;142(12):1650-1666. doi:10.1001/archderm.142.12.1663

Pseudomonas aeruginosa is usually isolated from chronic skin ulcers such as bed sores, but it can rarely cause cellulitis and, more rarely, facial cellulitis.14 While P aeruginosa has low to moderate virulence in healthy patients, in immunocompromised subjects, such as those with neutropenia, it acts as an opportunistic pathogen with severe and life-threatening complications. We report the case of a previously healthy woman who was seen with an ecthyma gangrenosum and severe facial cellulitis following carbimazole-induced agranulocytosis.

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