Calciphylaxis is an uncommon and extremely painful calcifying panniculitis, most often seen in patients with end-stage renal disease. The prognosis is poor, with a 6-month mortality rate ranging from 33% to 80%.1 Dermatologists are often called on to diagnose the condition, but unfortunately, successful treatments have not been available. We describe a case that responded to treatment with sodium thiosulfate.
Baker BL, Fitzgibbons CA, Buescher LS. Calciphylaxis Responding to Sodium Thiosulfate Therapy. Arch Dermatol. 2007;143(2):264-276. doi:10.1001/archderm.143.2.269