Histopathologic examination of lesional skin from one of the legs (Figure 3) and the back (Figure 4) showed globular deposits of homogeneous, eosinophilic material within the papillary dermis. The diagnosis of PLCA was confirmed by positive staining with Congo red. The patient noted relief from pruritus and flattening of the lesions on her legs after 4 weeks of treatment with clobetasol propionate ointment under occlusion.
Pruritic Patches on the Back and Papules on the Legs—Diagnosis. Arch Dermatol. 2007;143(2):255-260. doi:10.1001/archderm.143.2.255-g