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May 2007

Disseminated Cutaneous Kaposi Sarcoma and Progressive Multifocal Leukoencephalopathy in a Patient With Idiopathic CD4+ T Lymphocytopenia

Arch Dermatol. 2007;143(5):659-675. doi:10.1001/archderm.143.5.673

An 82-year-old white man presented with progressive, multilocalized skin lesions of more than 1 year's duration on the lower extremities (Figure, A and B) that had spread to the trunk. Histologic findings showed features of Kaposi sarcoma (KS) (Figure, C), which was confirmed by human herpesvirus 8 detection in KS and peripheral blood via polymerase chain reaction. Systemic malignancies, sarcoidosis, hypogammaglobulinemia, and dysgammaglobulinemia were excluded.

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