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Kittler et al1 found that after 4.5 months, 61.8% of melanomas did not show specific features of malignancy, and after 8.0 months, 35.1% of melanomas were not classifiable as melanoma without sequential dermoscopic examination. Therefore, the authors concluded that observations of change in the lesions can help the physician detect melanoma when there are no other visible signs of malignancy.
Carli P. Identification of Incipient Tumors by Means of Sequential Dermoscopy Imaging: A New Way to Inflate the “Epidemic” of Melanoma?. Arch Dermatol. 2007;143(6):799-816. doi:10.1001/archderm.143.6.805-a