Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2008
Gefitinib (Iressa; AstraZeneca, London, England) has been used in the treatment of non–small cell lung cancer (NSCLC).1 The cutaneous toxic effects associated with epidermal growth factor receptor (EGFR) inhibitors are follicular eruption, paronychia, and xerosis.2- 4 Herein, we describe 3 patients with reticular erythematous eruptions on the lower extremities associated with gefitinib.
Sheen Y, Hsiao C, Chu C. Severe Purpuric Xerotic Dermatitis Associated With Gefitinib Therapy. Arch Dermatol. 2008;144(2):269-270. doi:10.1001/archdermatol.2007.53