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February 1, 2008

Multiple Nodules in a Child—Diagnosis

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Arch Dermatol. 2008;144(2):255-260. doi:10.1001/archdermatol.2007.41-b

Results of histologic examination of the nodule revealed a lesion with an indistinct margin extending from the deep dermis to the fatty tissue. The nodule comprised spindle-shaped fibroblastlike cells intermingled with gangliocytelike giant cells with abundant eosinophilic cytoplasm and large nuclei with prominent nucleoli. The interstitium was primarily composed of a mucinous matrix with few collagen fibers. Typical mitoses were observed. Within 4 weeks, a spontaneous regression of all nodules was observed without any treatment; within 3 months, all the nodules completely disappeared.

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