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February 1, 2008

Psoriasiform Eruption and Pharyngitis—Diagnosis

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Arch Dermatol. 2008;144(2):255-260. doi:10.1001/archdermatol.2007.43-b

Histopathologic examination showed hyperkeratosis and psoriasiform hyperplasia of the epidermis and a dense plasma cell–rich infiltrate in the dermis. A Treponema pallidum–specific immunoperoxidase stain was intensely positive within the epidermis and dermis. Serologic findings were positive for the VDRL test and the T pallidum hemoagglutination assay (TPHA), with a dilution of 1:32 and 1:5120, respectively; findings were also positive for the treponemal antibody-absorption test. Neurologic evaluation and cerebrospinal fluid tests ruled out neurosyphilis. Total body tomographic scans excluded extracutaneous involvement.

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