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Pyoderma gangrenosum is an idiopathic, rapidly evolving, severely debilitating neutrophilic dermatosis, typically characterized by an inflammatory ulcer with a purulent infiltrated border.1 About two-thirds of pyoderma gangrenosum are associated with systemic diseases, mostly inflammatory bowel diseases (either ulcerative colitis or Crohn disease), but also with monoclonal gammapathies and myeloproliferative disorders.
Farhi D. The Clinical and Histopathological Description of Geometric Phagedenism (Pyoderma Gangrenosum) by Louis Brocq One Century Ago. Arch Dermatol. 2008;144(6):755. doi:10.1001/archderm.144.6.755