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Notable Notes
June 1, 2008

The Clinical and Histopathological Description of Geometric Phagedenism (Pyoderma Gangrenosum) by Louis Brocq One Century Ago

Arch Dermatol. 2008;144(6):755. doi:10.1001/archderm.144.6.755

Pyoderma gangrenosum is an idiopathic, rapidly evolving, severely debilitating neutrophilic dermatosis, typically characterized by an inflammatory ulcer with a purulent infiltrated border.1 About two-thirds of pyoderma gangrenosum are associated with systemic diseases, mostly inflammatory bowel diseases (either ulcerative colitis or Crohn disease), but also with monoclonal gammapathies and myeloproliferative disorders.

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