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July 21, 2008

Nodular Eruption on the Feet, Knees, and Dorsal Surface of the Hands of a 34-Year-Old HIV-Positive Man—Quiz Case

Author Affiliations
 

R. CUSACKCARRIE ANNMDW. DYSONSENAITMDM. JUNKINS-HOPKINSJACQUELINEMDLIUVINCENTMDS. ROSENMANKARLAMD

Arch Dermatol. 2008;144(7):933-938. doi:10.1001/archderm.144.7.933-c

A 34-year-old human immunodeficiency virus (HIV)– and hepatitis C–positive man developed disfiguring nodules on his feet, hands, and knees over a 3-month period. The individual lesions were asymptomatic; however, the bulkiness of the lesions on his feet impeded ambulation. His CD4 lymphocyte count was 170/μL (reference range, 490/μL-1740/μL), and his HIV viral load was more than 105 copies/μL. Serologic tests were negative for serum cryptococcal antigen and rapid plasmin reagin. His medications were tenofovir plus emtricitabine, atazanavir, trimethoprim-sulfamethoxazole, fluconazole, paroxetine hydrochloride, venlafaxine, methadone, and fentanyl.

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