[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.197.75.176. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Editorial
September 15, 2008

Dermoscopy and the Diagnostic Challenge of Amelanotic and Hypomelanotic Melanoma

Arch Dermatol. 2008;144(9):1207-1210. doi:10.1001/archderm.144.9.1207

In this issue of the Archives, Menzies et al1 analyze a large number of hypopigmented lesions to determine the most useful dermoscopic features for detection of amelanotic and hypomelanotic melanoma (AHM). Dermoscopy, which uses magnification with a glass plate and fluid or with cross-polarized lighting, improves diagnostic accuracy for pigmented lesions.2 For clinical observation without dermoscopy, diagnostic sensitivity and specificity of AHM have been reported as 65% and 88%, respectively3; however, dermoscopy improves sensitivity and specificity to 89% and 96%, respectively.3 For truly amelanotic melanomas, diagnosis depends critically on vascular patterns, which are visible only by dermoscopy.

First Page Preview View Large
First page PDF preview
First page PDF preview
×