MARY S.STONEMDSOONBAHRAMIMDCARRIE ANN R.CUSACKMDSENAIT W.DYSONMDMOLLY A.HINSHAWMDVINCENTLIUMD
At low power, the skin biopsy specimen showed hyperplasia in the epidermis and dense perivascular and periadnexal infiltrate in the dermis with a slightly nodular pattern. At high power, there was dense infiltration of inflammatory cells, including lymphocytes and plasma cells.
Laboratory tests revealed a positive reaction to venereal disease research laboratory (VDRL) slide testing. Further laboratory tests showed a positive reaction to assays for fluorescent treponemal antibody absorption (FTA-ABS), FTA-ABS IgM, and Treponema pallidum hemagglutination (TPHA). The VDRL titer was over 1:32. Immunohistochemical analysis with a polyclonal antibody, anti–T pallidum, was performed, and many spirochetes were found.
Erythematous Erosive Patch on the Left Nipple—Diagnosis. Arch Dermatol. 2010;146(1):81-86. doi:10.1001/archdermatol.2009.335-b