Mesotherapy, or the transcutaneous injection of compounds for local treatment of a medical condition or for cosmesis, is an emerging trend in skin rejuvenation. Despite the relative paucity of published clinical trials assessing the efficacy of mesotherapy for cosmesis,1 mesotherapy is performed by both licensed and unlicensed practitioners in the United States and abroad. Little has been discussed regarding adverse reactions to vitamins administered transcutaneously for cosmesis. We report herein an adverse cutaneous reaction to injection of the contents of a vitamin E capsule, and we describe its course and histologic correlates.
Pugliese S, Yaar R, Al-Dawsari N, Goldberg LJ, Garg A. Adverse Reaction to Cutaneous Injection of Contents From a Vitamin E Liquid–Containing Capsule. Arch Dermatol. 2010;146(4):454-455. doi:10.1001/archdermatol.2010.30