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April 2010

An Erythematous Plaque Filled With Open and Closed Comedones—Quiz Case

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Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Dermatol. 2010;146(4):439-444. doi:10.1001/archdermatol.2010.38-a

A 52-year-old man presented with a 2-week history of a pruritic plaque on the central area of his chest. His medical history was remarkable for stage IV metastatic esophageal cancer, for which he had received 6 cycles of cisplatin and irinotecan hydrochloride and 3000 rads (to convert to grays, multiply by 0.01) of radiotherapy. He did not receive additional chemotherapy. His skin lesion developed within the radiation port 3 months after he completed radiation therapy. The area was treated with topical sulfadiazine silver (Silvadene), without improvement. The patient denied use of oral steroids, exposure to halogenated compounds, or severe acne as an adolescent.

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