Citations 0
May 2010

Pyoderma Gangrenosum Presenting With Leukemoid Reaction: A Report of 2 Cases

Author Affiliations

Author Affiliations: Harvard Medical School (Dr Ryu), Harvard Combined Dermatology Residency Training Program (Dr Naik), and Department of Dermatology, Brigham and Women's Hospital (Drs Yang and Winterfield), Boston, Massachusetts.


Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Dermatol. 2010;146(5):568-569. doi:10.1001/archdermatol.2010.80

A 46-year-old woman underwent fine-needle aspiration of her left breast. Within a week, she developed erythema and swelling at the biopsy site. Despite treatment with oral antibiotics and 5 surgical debridements, her wounds continued to expand, and she developed fever and leukocytosis (peak white blood cell count [WBC], 74 000/μL with 12% bands) as well as hypotension, hyponatremia, and acute renal failure. (To convert white blood cells to number of cells ×109/L, multiply by 0.001.) She also developed new erythema at a catheter insertion site in her right arm. This wound was debrided, yielding negative cultures.

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