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October 2010

Moist Toilet Paper: Allergy to the Nonhalogenated Derivative Methylisothiazolinone Preservative Alone

Author Affiliations

Author Affiliations: Departments of Dermatology, University Hospital Complex, Faculty of Medicine, University of Santiago de Compostela, A Coruña, Spain (Dr García-Gavín), and University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium (Dr Goossens).


Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Dermatol. 2010;146(10):1186. doi:10.1001/archdermatol.2010.279

We read with great interest the article by Gardner et al1 in the August issue of the Archives. In our opinion, the authors fail to distinguish between 2 different preservatives: the mixture in a 3:1 ratio of methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and the nonhalogenated derivative MI alone, which is, according to the article, contained in Cottonelle moist toilet paper (Kimberly-Clark Corporation, Neenah, Wisconsin).

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