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December 20, 2010

Erythroderma and Spontaneous Blistering in a 49-Year-Old Man—Quiz Case

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Arch Dermatol. 2010;146(12):1419-1424. doi:10.1001/archdermatol.2010.359-a

A 49-year-old man with acute hemorrhagic stroke and subsequent hemicraniectomy presented with an abrupt onset of skin blistering of the bilateral upper extremities, flanks, and upper part of the thighs on hospital day 17. His postoperative course was complicated by persistent low-grade fevers and methicillin-resistant Staphylococcus aureus pneumonia. In the 2 weeks before the blistering began, he had been treated with several new medications, including piperacillin-tazobactam, trimethoprim-sulfamethoxazole, vancomycin, and furosemide.

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