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Evidence-Based Dermatology: Research Commentary
June 20, 2011

Isotretinoin Therapy and Inflammatory Bowel Disease

Author Affiliations
 

MICHAELBIGBYMDOLIVIERCHOSIDOWMD, PhDROBERT P.DELLAVALLEMD, PhD, MSPHDAIHUNGDOMDURBGONZLEZ, MD, PhDAgraveAacuteLEZ, MD, PhDCATALIN M.POPESCUMD, PhDHYWELWILLIAMSMSc, PhD, FRCP

Arch Dermatol. 2011;147(6):724-729. doi:10.1001/archdermatol.2011.116

Crockett SD, Gulati A, Sandler RS, Kappelman D

Am J Gastroenterol. 2009;104(10):2387-2393.

Question: Is oral isotretinoin use associated with the development of inflammatory bowel disease (IBD)?

Design: Critical appraisal of published case reports and case series using the Hill criteria for causality.

Data Sources: Data were obtained from a systematic search of published case reports and case series.

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