MARY S.STONEMDSOONBAHRAMIMDCARRIE ANN R.CUSACKMDSENAIT W.DYSONMDMOLLY A.HINSHAWMDARNI K.KRISTJANSSONMD
Histopathologic examination revealed epidermal spongiosis and liquefactive necrosis of the upper dermis admixed with numerous amebic trophozoites (Figure 2). The trophozoites were identified by the eccentric small nuclei with a central karyosome and abundant cytoplasm with vacuolation and ingested erythrocytes (Figure 3). The patient was thought to have a disseminated cytomegalovirus infection and was treated with intravenous ganciclovir sodium for 2 weeks. She also received intravenous meropenem. Her condition deteriorated, however, and she died before the diagnosis of invasive amebiasis was made by means of histopathologic examination and tissue culture.
Erythema Nodosum–Like Lesions in a Renal Transplant Recipient—Diagnosis. Arch Dermatol. 2011;147(6):735-740. doi:10.1001/archdermatol.2011.128-b