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Erosive pustular dermatosis of the scalp (EPDS) is a rare disorder of elderly people with actinically damaged skin. It is characterized by multiple pustules, erosions, and crusts on the scalp that can result in scarring alopecia.1 Although the cause remains unknown, there is often a history of previous trauma such as cryotherapy, radiotherapy, laser treatment, surgery, photodynamic therapy, or irritant contact dermatitis such as that caused by topical treatments with fluorouracil, imiquimod, or tretinoin.
Darwich E. Erosive Pustular Dermatosis of the Scalp Responding to Acitretin. Arch Dermatol. 2011;147(2):252-253. doi:10.1001/archdermatol.2010.442