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March 2011March 21, 2011

Persistent Skin Lesions in a 75-Year-Old Man—Diagnosis

Author Affiliations
 

MARY S.STONEMD

 

SOONBAHRAMIMDCARRIE ANN R.CUSACKMDSENAIT W.DYSONMDMOLLY A.HINSHAWMDARNI K.KRISTJANSSONMD

Arch Dermatol. 2011;147(3):345-350. doi:10.1001/archdermatol.2011.35-b

Low-power (×200) hematoxylin-eosin staining of the biopsy specimen showed a normal epidermis with the Grenz zone above a granulomatous infiltrate of the dermis (Figure 2). Higher-power (×600) examination showed that the inflammatory infiltrate of the dermis extended down around the periadnexa and perieccrine glands with involvement of the small nerves present in the biopsy specimen. Fite staining of the tissue revealed globi containing numerous small, filamentous, acid-fast organisms consistent with leprosy bacilli (Figure 3). The combined clinical presentation and histologic findings confirmed a diagnosis of lepromatous leprosy.

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