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May 16, 2011

Painful Swollen Foot—Diagnosis

Author Affiliations
 

MARY S.STONEMDSOONBAHRAMIMDCARRIE ANN R.CUSACKMDSENAIT W.DYSONMDMOLLY A.HINSHAWMDARNI K.KRISTJANSSONMD

Arch Dermatol. 2011;147(5):609-614. doi:10.1001/archdermatol.2011.90-b

Findings from microscopic examination with hematoxylin-eosin–stained sections showed fragments of trabecular bone with intervening fibrosis and acute and chronic inflammation consistent with osteomyelitis. A few scattered and amorphous, nonpigmented structures suggestive of granules were identified. Gomori methenamine silver–stained sections showed that these structures were composed of tightly packed aggregates of septated and branching hyphae. Tissue bacterial and acid-fast bacilli cultures were negative for organisms. The fungal culture grew Pseudallescheria boydii.

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