Satoyoshi syndrome (SS) is a rare disorder of unknown cause characterized by progressive, painful, intermittent muscle spasms, diarrhea or unusual malabsorption, endocrinopathy with amenorrhea, secondary skeletal abnormalities, and especially alopecia areata. We report a case of SS and review the clinical features.
A 24-year-old Japanese woman presented with symptoms of fever, abdominal pain, diarrhea, amenorrhea, and alopecia universalis (Figure 1). Intermittent muscle spasms of her whole body occurred several times per hour at irregular intervals.
Oyama M, Imaizumi T, Mitsuhashi Y, Kondo S. Satoyoshi Syndrome. Arch Dermatol. 1999;135(1):91-92. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-1-dlt0199