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January 1999

Bullous Eruption in a 36-Year-Old Man With Polycystic Kidney Disease

Arch Dermatol. 1999;135(1):81-a-86. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-1-dof0199

Hematoxylin-eosin–stained sections showed a cell-poor, subepidermal bulla with festooning of the dermal papillae. Periodic acid–Schiff staining showed thickened papillary dermal vessel walls and the basement membrane zone at the floor of the bulla. Direct immunofluorescence sections of lesional skin showed moderate, diffuse deposition of IgG and IgA at the superficial papillary vessel walls and at the dermoepidermal junction; focal linear and granular deposition of complement (C3) at the dermoepidermal junction; and mild diffuse deposition of fibrinogen at the superficial papillary vessel walls.

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