Keloids and hypertrophic scars are common problems affecting 4.5% to16% of the general population.1 The treatment for this skin problem can be difficult. Laser ablation, surgical removal, irradiation, intralesional corticosteroid or interferon injections, silicone cream or gel application, cryotherapy, and occlusive dressing have all been used either alone or in various combinations with variable but largely transient success. Recently, UV-A1 (340-400 nm) has received much attention as a possible treatment for atopic dermatitis,2 morphea,3 and scleroderma.4,5 Given the in vitro work regarding the effect of UV-A1 on stimulated collagenase production by fibroblasts, we decided to use UV-A1 phototherapy to treat a keloid. We report on the success of our treatment in this challenging clinical scenario.
Asawanonda P, Khoo LSW, Fitzpatrick TB, Taylor CR. UV-A1 for Keloid. Arch Dermatol. 1999;135(3):348-349. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-3-dlt0399